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. Author manuscript; available in PMC: 2020 Jun 19.
Published in final edited form as: J Comp Neurol. 2018 Aug 8;526(13):2115–2132. doi: 10.1002/cne.24496

Table 3:

Number of neurons in the different layers of the entorhinal cortex in rats and humans

Layer II Layer III Layer V + VI All layers
Mean SD Mean SD Mean SD Mean SD
Rat MEC 62,924 140,541 184,625 388,090
1 66,400 10,383 128,200 16,423 185,400 24,419 380,000 36,871
2 59,448 8,575 152,881 15,122 183,849 23,490 396,178 29,223
Rat LEC 40,896 112,335 134,546 287,777
1 45,600 13,278 119,400 15,502 143,800 29,575 308,800 44,673
2 36,192 6,133 105,269 18,538 125,291 24,120 266,752 31,034
Rat EC 103,820 252,875 319,170 675,865
1 112,000 22,327 247,600 22,843 329,200 53,844 688,800 76,594
2 95,640 10,543 258,150 23,294 309,140 33,668 663,000 46,000
Monkey EC 499,784 64,505 1,621,012 102,823 1,411,615 145,832 3,532,411 252,997
Human EC 652,500 3,590,500 3,247,500 7,490,500
3 647,000 143,066 3,525,000 623,810 2,711,000 619,757 6,883,000 1,136,076
4 658,000 107,098 3,656,000 570,640 3,784,000 288,929 8,098,000 875,825
1

Mulders et al., 1997. The Journal of Comparative Neurology, 385:83–94.

2

Merrill et al., 2001. The Journal of Comparative Neurology, 438:445–456.

3

Gomez-Isla et al.,1996. Journal of Neuroscience, 16(14):4491–4500.

4

West and Slomianka, 1998. Hippocampus, 8:69–82 + 8:426 corrigendum.