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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Traffic. 2020 Apr 29;21(6):404–418. doi: 10.1111/tra.12730

Figure 1: Mechanisms of RNA localization.

Figure 1:

A) Local RNA transcriptomes are established in neurons to facilitate local protein production in response to stimuli. RNA binding proteins are essential for transport of these RNAs. B) RNAs are transported along cytoskeletal networks in various cell types. Short range transport is typically mediated by actin filaments and myosins, which can facilitate retrograde and anterograde movement. Long range transport is achieved with microtubules in both retrograde and anterograde movement using dynein and kinesin, respectively. C) Concentration gradients of RNAs are established using anchors composed of proteins that sequester RNA.