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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Traffic. 2020 Apr 29;21(6):404–418. doi: 10.1111/tra.12730

Figure 2: Misregulation of RNA localization is relevant to disease phenotypes.

Figure 2:

A) RNA localization patterns to various subcellular compartments are disrupted in various diseases. B) Establishment of EMT is associated with RNA localization changes. C) Gradients of RNA concentrations are observed between the apical and basal axis of epithelial cells; however, it is not clear if disruption of these patterns contributes to disease phenotypes. D) Asymmetric distribution of RNAs helps establish developmental states and disruption of these patterns contributes to establishment of cancer.