Table 3.

Cohen’s d effect sizes for group comparisons of slope from months 2-36 for GCP and selected individual neuropsychological tests

	Effect size: Cohen’s d
Group:	HVLT total learning	HVLT delayed recall	Trails B	GCP
AD signature Tertiles [reference group: AD signature Tertile 1 (n=45)]
AD signature Tertile 2 (n=47)	−0.20	−0.05	−0.32	−0.26
AD signature Tertile 3 (n=48)	−0.13	−0.32	−0.66	−0.40
AD signature Tertiles and Delirium [(reference group: AD signature Tertile 1, no delirium (n=35)]
AD signature Tertile 2, no delirium (n=38)	−0.10	0.02	−0.40	−0.31
AD signature Tertile 3, no delirium (n=37)	0.11	−0.23	−0.66	−0.25
AD signature Tertile 1, delirium (n=13)	0.08	−0.01	−0.16	−0.03
AD signature Tertile 2, delirium (n=9)	−0.44	−0.34	−0.09	−0.11
AD signature Tertile 3, delirium (n=8)	−1.13	−0.83	−1.16	−1.10

Cohen’s d effect size interpretation: small (d ≥ 0.2), medium (d ≥ 0.5), large (d≥0.8); medium to large effect sizes are bolded.

GCP = General Cognitive Performance; HVLT = Hopkins Verbal Learning Test–Revised; Trails B = Trail Making Test B