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. Author manuscript; available in PMC: 2020 Jun 19.
Published in final edited form as: Eur J Cancer. 2015 Jul 31;51(14):1978–1988. doi: 10.1016/j.ejca.2015.07.012

Table 2.

Risk factors for venous thromboembolism in our cohort (n = 1308).

Variable No. 2-Year cumulative rate, % Univariate
Multivariate
HR (95%CI) P-valuea HR (95%CI) P-valuea
Age 0.009 0.016
 <60 years 705 14.1 1 1
 ⩾60 years 603 19.3 1.42 (1.09–1.86) 1.46 (1.07–1.99)
CA-125 levels 0.003 0.025
 ⩽35 IU/L 132   5.8 1 1
 >35 IU/L 1061 17.0 2.52 (1.33–4.76) 2.38 (1.11–5.07)
Thrombocytosisb 0.0001 0.032
 No 860 13.8 1 1
 Yes 434 22.3 1.66 (1.26–2.18) 1.42 (1.03–1.96)
Residual tumour size after surgery 0.028 0.52
 >1 cm 353 20.2 1 1
 ⩽4 cm 897 13.6 0.72 (0.53–0.97) 0.89 (0.63–1.27)
Stage-specific histologic type <0.0001
 Advanced SOC 836 16.2 1 1
 Advanced OCCC 106 43.1 2.74 (1.92–3.92) 3.38 (2.28–5.01) <0.0001
 Early-stage SOC 102   6.4 0.54 (0.28–1.03) 0.80 (0.38–1.68) 0.55
 Early-stage OCCC 264 11.9 0.73 (0.50–1.06) 1.23 (0.77–1.95) 0.39

Abbreviations: HR, hazard ratio; CI, confidence interval; CA-125, cancer antigen 125; SOC, serous ovarian carcinoma; OCCC, ovarian clear cell carcinoma.

a

The log-rank test was used for univariate analysis and Cox proportional hazards regression modelling was used for multivariate analysis.

b

Platelet count ⩾ 400 × 109/L.