Figure 6.

(A) UV–vis spectra for the determination of covalent IMDQ loading to ketal- and ether-cross-linked nanogels as well as non-cross-linked soluble polymers derived from poly(Pfp-Nb)₅₀-b-poly(mPEG-Nb)₅₀ precursor micelles. (B) DLS measurements of the IMDQ-loaded nanogels and polymers in PBS, compared to the nonloaded species. (C) Results of the TLR stimulation of RAW-Blue macrophages treated with the poly(norbornene)-derived imidazoquinoline nanocarriers (n = 4). (D) Results of the TLR stimulation assay of poly(methacrylamide) carriers (n = 4).