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. 2020 Apr 19;22(9):3734–3738. doi: 10.1021/acs.orglett.0c01238

Table 1. Double Tsuji–Trost Allylation Reactions of bis-Carbonate 16 Catalyzed by Palladium Complexes of Ligands 17ac.

    Product ratioa
 
Entry Ligand 18a 18b 18c 18d Yieldb
1 17c 45 9 46
2 17a 40 49 11 75%
3 17b 37 63 70%
4 (±)-17a/b 42 7 51
a

Ratio of diastereomeric products 18ad determined by 1H NMR analysis of crude material.

b

Combined yield of diastereomeric products 18 isolated by chromatography.