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. 2020 Jun 11;79(7):719–733. doi: 10.1093/jnen/nlaa046

TABLE.

Distinguishing Type I From Type II Muscle Fibers

Muscle Fiber Type Type I Type II
Predominant actions
  • Sustained force

  • Weight-bearing

  • Sudden movement

  • Purposeful motion

Physiology Slow twitch Fast twitch
Predominant myosin (gene)
  • Slow myosin heavy chain (MHC)

  • (MYH7)

  • Fast MHC

  • (MYH2)

Typically stain darker
  • ATPase pH 4.2

  • Nicotinamide adenine dinucleotide

  • Succinate dehydrogenase

  • Cytochrome C oxidase

ATPase pH 9.4
Glycogen Less More (glycolytic metabolism)
Mitochondria More numerous Less numerous
Neutral lipid More (oxidative metabolism) Less
Meat color (e.g. domestic fowl) Red (dark) White

“One mighty slow fat red ox.” Mnemonic used to recall features of type I muscle fibers first learned from mentor Robert Schelper, circa 1984.