Table 1.
Baseline characteristics in ACCORD by incident HF status
| No HF (n = 9,070) | HF (n = 313) | P value | |
|---|---|---|---|
| Age (years) | 62.6 (6.5) | 65.5 (6.8) | <0.001 |
| Intensive BP treatment (% yes) | 2,105 (23.2) | 58 (18.5) | 0.06 |
| Female (% yes) | 3,507 (38.7) | 96 (30.7) | 0.005 |
| Race/ethnicity (%) | 0.001 | ||
| White | 5,634 (62.1) | 217 (69.3) | |
| Black | 1,707 (18.8) | 64 (20.4) | |
| Hispanic | 654 (7.2) | 15 (4.8) | |
| Other | 1,075 (11.9) | 17 (5.4) | |
| Diabetes duration (years) | 10.6 (7.5) | 12.8 (8.4) | <0.001 |
| History of CVD (% yes) | 2,912 (32.1) | 177 (56.5) | <0.001 |
| Smoker† (% yes) | 4,034 (51.0) | 163 (60.1) | 0.004 |
| BMI (kg/m2) | 32.1 (5.4) | 33.2 (5.6) | 0.001 |
| DBP (mmHg) | 75 (10) | 73 (11) | <0.001 |
| SBP (mmHg) | 136 (17) | 139 (19) | 0.001 |
| HDL cholesterol (mg/dL) | 42 (12) | 39 (11) | <0.001 |
| LDL cholesterol (mg/dL) | 105 (34) | 102 (34) | 0.15 |
| Total cholesterol (mg/dL) | 183 (42) | 179 (41) | 0.06 |
| Triglycerides (mg/dL) | 190 (150) | 197 (127) | 0.37 |
| HbA1c (%) | 8.3 (1.1) | 8.6 (1.1) | <0.001 |
| UACR (mg/g) | 88.8 (337.1) | 260.7 (666.0) | <0.001 |
| eGFR (mL/min/1.73 m2) | 91.8 (27.3) | 84.8 (23.4) | <0.001 |
Continuous data are presented as the mean (SD) and categorical data as indicated. At 1 year, HbA1c values of 6.4% and 7.5% were achieved in intensive and standard groups, respectively, and remained relatively stable thereafter. eGFR was calculated from the four-variable MDRD Study equation. BP, blood pressure.
†
Smoker: smoked >100 cigarettes during lifetime.