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. 2020 Mar 24;196(7):637–646. doi: 10.1007/s00066-020-01605-z

Table 4.

Outcome after salvage lymph node dissection/salvage lymph node radiotherapy

SLND cohort
(n = 33)
SLNRT cohort
(n = 67)
p-value
Median follow-up (months) 17 (6–53) 31 (3–56) 0.027
Posttreatment PSA (ng/ml) 0.47 (<0.03–9.61) 0.05 (<0.03–19.0) 0.003
PSA at last follow-up (ng/ml)
Median PSA (range) 2.50 (<0.03–68.0) 0.05 (<0.03–268) 0.025
PSA ≤0.1 ng/ml 7 (21%) 46 (69%) 0.001
PSA ≤0.2 ng/ml 10 (30%) 50 (75%) 0.001
PSA at last follow-up without ADT (ng/ml) n = 25 n = 42
Median PSA 1.21 (<0.03–13.0) 0.06 (<0.03–268) 0.02
PSA ≤0.1 ng/ml 5 (20%) 32 (76%) 0.001
PSA ≤0.2 ng/ml 7 (28%) 34 (81%) 0.001
Secondary treatment (ADT, RT, sx) 13 (39%) 10 (15%) 0.011
Clinical progress
Distant metastases 17 (52%) 14 (21%) 0.002
Death 0 3 0.549
Tumour-related 0 1 1.0

SLND salvage lymph node dissection, SLNRT salvage lymph node radiotherapy, ADT androgen deprivation therapy, PSA prostate specific antigen, RT radiotherapy, sx surgery