Table 4.
Outcome after salvage lymph node dissection/salvage lymph node radiotherapy
| SLND cohort (n = 33) |
SLNRT cohort (n = 67) |
p-value | |
|---|---|---|---|
| Median follow-up (months) | 17 (6–53) | 31 (3–56) | 0.027 |
| Posttreatment PSA (ng/ml) | 0.47 (<0.03–9.61) | 0.05 (<0.03–19.0) | 0.003 |
| PSA at last follow-up (ng/ml) | |||
| Median PSA (range) | 2.50 (<0.03–68.0) | 0.05 (<0.03–268) | 0.025 |
| PSA ≤0.1 ng/ml | 7 (21%) | 46 (69%) | 0.001 |
| PSA ≤0.2 ng/ml | 10 (30%) | 50 (75%) | 0.001 |
| PSA at last follow-up without ADT (ng/ml) | n = 25 | n = 42 | |
| Median PSA | 1.21 (<0.03–13.0) | 0.06 (<0.03–268) | 0.02 |
| PSA ≤0.1 ng/ml | 5 (20%) | 32 (76%) | 0.001 |
| PSA ≤0.2 ng/ml | 7 (28%) | 34 (81%) | 0.001 |
| Secondary treatment (ADT, RT, sx) | 13 (39%) | 10 (15%) | 0.011 |
| Clinical progress | |||
| Distant metastases | 17 (52%) | 14 (21%) | 0.002 |
| Death | 0 | 3 | 0.549 |
| Tumour-related | 0 | 1 | 1.0 |
SLND salvage lymph node dissection, SLNRT salvage lymph node radiotherapy, ADT androgen deprivation therapy, PSA prostate specific antigen, RT radiotherapy, sx surgery