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. 2020 Jun 19;10:9972. doi: 10.1038/s41598-020-65306-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Minimal therapeutic effect of the mixture of SO components including CA, GA, EA, ZY (Mix₄) on suppression of DSS-induced colitis in Atg7^LysM-cre mice. Atg7^f/f and Atg7^LysM-cre mice were administered 2% DSS with or without Mix₄ for 7 days. (a) Weight changes, (b) colon length, (c) representative colon sections (upper), and histological score of the colon (bottom). Data are mean ± SD of five mice in each group. *p < 0.05. n.s., not significant. Bars; 100 μm. Data are of two independent experiments.