Table 1.
Brain Donor Characteristics.
| Brain | Group | Gender | Age | PMI | Source | MECP2 | |
|---|---|---|---|---|---|---|---|
| NM_004992.3 | |||||||
| cDNA | Protein | ||||||
| 1038 | CTL | F | 24 | 7 | NBB | NA | NA |
| 1614 | CTL | F | 27 | 18 | NBB | NA | NA |
| 4724 | CTL | F | 16 | 15 | NBB | NA | NA |
| 4725 | CTL | F | 32 | 17 | NBB | NA | NA |
| 6355 | RTT | F | 16 | 28 | HBTRC | NR | NR |
| 7773 | RTT | F | 24 | 25 | HBTRC | c.473 C > T | p.Thr158Met |
| 7783 | RTT | F | 26 | 39 | HBTRC | Exon Del | |
| B7992 | RTT | F | 31 | 30 | HBTRC | NR | NR |
Abbreviations: CTL, control; F, female; HBTRC, Harvard Brain Tissue Resource Center; NA, not applicable; NBB, NIH NeuroBioBank; NR, no mutation in MECP2 reported; PMI, postmortem interval in hours; RTT, Rett syndrome.