Table 1.
Patient characteristics by treatment regimen
| Characteristics | Conventional fractionation (72–78 Gy in 2.0 Gy fractions) |
Hypofractionation (60 Gy in 3.0 Gy fractions) |
|---|---|---|
| No. of patients | 55 | 55 |
| Age, years | ||
| <65 | 2 (3.6) | 3 (5.4) |
| 65–74 | 12 (21.8) | 8 (14.5) |
| 75–79 | 30 (54.5) | 20 (36.4) |
| ≥80 | 11 (20.0) | 24 (43.6) |
| Tumor stage | ||
| T1–T1c | 44 (80.0) | 45 (81.8) |
| T2 a–b | 5 (9.1) | 6 (10.9) |
| ≥T2c | 6 (10.9) | 4 (7.3) |
| Gleason score | ||
| ≤6 | 9 (16.4) | 7 (12.7) |
| 7 | 27 (49.1) | 23 (41.8) |
| ≥8 | 19 (34.5) | 25 (45.5) |
| D’Amico risk classification | ||
| Low | 4 (7.3) | 3 (5.5) |
| Intermediate | 28 (50.9) | 27 (49.1) |
| High | 23 (41.8) | 25 (45.5) |
| Charlson comorbidity index (CCI) | ||
| ≤3 | 26 (47.3) | 18 (32.7) |
| 4 | 15 (27.3) | 14 (25.5) |
| 5 | 7 (12.7) | 8 (14.6) |
| 6 | 3 (5.5) | 8 (14.6) |
| ≥7 | 4 (7.3) | 7 (12.7) |
| ADT | ||
| Yes | 25 (45.5) | 31 (56.4) |
| No | 30 (54.5) | 24 (43.6) |
| Nicotine | ||
| Yes | 3 (5.5) | 10 (18.2) |
| Alcohol | ||
| Yes | 15 (27.3) | 17 (30.9) |
| Medication | ||
| Anticoagulants | 21 (38.1) | 16 (29.1) |
| Antiplatelet agents | 13 (23.6) | 20 (36.4) |
| Non-antithrombotic drugs | 41 (74.5) | 40 (72.7) |
Data are given in no.; % in parenthesis. Table shows the baseline characteristics in HRT and CRT groups
ADT androgen deprivation therapy, HRT hypofractionated radiation therapy, CRT conventional radiation therapy