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GW9508 inhibits AGE-induced activation of NF-κB. Cells were treated with AGEs (100 μg/mL) in the presence or absence of GW9508 (25 and 50 μM) for 6 h. (A) Nuclear translocation of NF-κB p65; (B) Luciferase activity of NF-κB (***, P<0.0001 vs. control group; *, **, P<0.01, 0.001 vs. AGE treatment group).
