Table 1.
Recommended surgical strategies for appendiceal NETs based on specific clinical and histological characteristics. Reprinted from Griniatsos, Michail, WJGO 2010 [11].
| Indications | Type of operation |
|---|---|
| Tumour size <1 cm | Appendicectomy |
| Tumour size 1–2 cm | Appendicectomy + Regular F/Up for 5 years |
| Tumour size >2 cm | Right hemicolectomy |
| Location of the tumour at the base of the appendix | Right hemicolectomy |
| Infiltration of the cecum | Right hemicolectomy |
| Positive surgical resection margins | Right hemicolectomy |
| Appendiceal mesentery invasion | Right hemicolectomy |
| Metastatically infiltrated mesoappendiceal lymph node | Right hemicolectomy |
| Presence of undifferentiated or low differentiated cells | Right hemicolectomy |
| Presence of goblet cells | |
| Goblet cell carcinoma in males | Right hemicolectomy |
| Goblet cell carcinoma in females (regardless of age) | Right hemicolectomy + Bilateral salpingo-oophorectomy |
| Peritoneal dissemination from goblet cell carcinoma | Cytoreductive surgery + Adjuvant intraperitoneal chemotherapy |