Table 4.
National | Nairobi region | Central region | Coast region | |||||
---|---|---|---|---|---|---|---|---|
Baseline | Intervention | Baseline | Intervention | Baseline | Intervention | Baseline | Intervention | |
ART coverage | ||||||||
Proportion of people living with HIV on ART in 2033 | 68.26% | 88.21% | 67.88% | 87.39% | 68.71% | 87.50% | 63.71% | 85.75% |
Total number on ART from 2019 to 2033 (million) |
37.46 [32.20 to 53.10] |
45.86 [38.3 to 62.70] |
4.87 [4.20 to 6.90] |
5.94 [5.00 to 8.10] |
2.78 [2.40 to 3.90] |
3.36 [2.80 to 4.60] |
2.98 [2.60 to 4.20] |
3.56 [3.00 to 4.90] |
Additional person year on ART (million) |
8.40 [6.20 to 10.10] |
1.07 [0.80 to 1.30] |
0.58 [0.40 to 0.70] |
0.58 [0.40 to 0.70] |
||||
HIV incidence (per 1000/year) | ||||||||
2018 |
0.97 [0.59 to 1.68] |
1.09 [0.67 to 1.89] |
0.66 [0.40 to 1.14] |
1.06 [0.65 to 1.84] |
||||
2033 |
0.72 [0.52 to 1.37] |
0.35 [0.28 to 0.59] |
0.81 [0.59 to 1.54] |
0.39 [0.31 to 0.65] |
0.51 [0.37 to 0.97] |
0.25 [0.20 to 0.42] |
0.83 [0.60 to 1.58] |
0.39 [0.31 to 0.65] |
% Reduction |
25.77% [7.10% to 45.48%] |
63.92% [48.29% to 66.06%] |
25.69% [7.07% to 45.33%] |
64.22% [48.52% to 66.37%] |
22.73% [6.26% to 40.11%] |
62.12% [46.93% to 64.20%] |
21.7% [5.98% to 38.29%] |
63.21% [47.76% to 65.32%] |
HIV prevalence | ||||||||
2018 |
3.35% [2.87% to 4.26%] |
4.23% [3.62% to 5.37%] |
2.65% [2.27% to 3.37%] |
3.19% [2.73% to 4.05%] |
||||
2033 |
2.43% [1.80% to 3.78%] |
2.33% [1.73% to 3.62%] |
2.99% [2.22% to 4.65%] |
2.88% [2.14% to 4.48%] |
2.03% [1.51% to 3.16%] |
1.96% [1.45% to 3.05%] |
2.37% [1.76% to 3.69%] |
2.15% [1.60% to 3.34%] |
% Reduction |
27.55% [20.50% to 30.62%] |
30.39% [26.58% to 32.33%] |
29.35% [21.84% to 32.62%] |
31.89% [27.89% to 33.93%] |
23.41% [17.42% to 26.01%] |
25.99% [22.73% to 27.65%] |
25.54% [19.00% to 28.28%] |
32.53% [28.45% to 34.61%] |
New HIV infections | ||||||||
Total from 2019 to 2033 (thousands) |
734.27 [521.75 to 1,261.79] |
387.55 [317.42 to 637.93] |
87.01 [61.82 to 149.52] |
44.87 [36.75 to 73.85] |
49.45 [35.13 to 84.97] |
25.7 [21.05 to 42.30] |
71.28 [50.64 to 122.49] |
36.56 [29.94 to 60.18] |
Infections averted (thousands) |
346.73 [196.79 to 629.64] |
42.15 [23.92 to 76.54] |
23.76 [13.48 to 43.15] |
34.72 [19.70 to 63.05] |
||||
Infections averted per additional ART person/year | 0.041 | 0.039 | 0.041 | 0.06 | ||||
HIV deaths | ||||||||
Total from 2019 to 2033 (thousands) |
544.61 [449.49 to 619.60] |
255.86 [217.87 to 295.29] |
69.54 [57.39 to 79.11] |
32.82 [27.94 to 37.88] |
41.76 [34.46 to 48.51] |
21.77 [18.53 to 25.12] |
45.13 [37.24 to 51.34] |
23.91 [20.36 to 27.59] |
Deaths averted (thousands) |
288.76 [231.79 to 342.25] |
36.72 [29.47 to 43.52] |
19.99 [16.04 to 23.69] |
21.22 [17.03 to 25.15] |
||||
Deaths averted per additional ART person/year | 0.034 | 0.034 | 0.034 | 0.036 |
HIV‐related outcomes are projected by the Spectrum model for the baseline and intervention at a national and regional level. Models are initialized with a similar population in 2018 and are followed to year 2033. The baseline scenario assumes a fixed ART coverage at 2018 levels over time. The intervention scenario models a gradual increase in coverage of ART from 2019 to 2023 [assuming a fixed coverage afterwards, from year 2024 to 2033). Values represents the median value [95% uncertainty ranges]. Uncertainty ranges are estimated across 1000 random simulations (generated by permuting epidemiological and behaviour parameters), weighted and resampled based on goodness of fit to the historical prevalence data(see Section 1.4 in Data S1).