Table 1.
Comparisons of mean corpuscular volume (MCV) and mean blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, and homocysteine levels between any two of three groups of 170 burning mouth syndrome (BMS) patients with hyperhomocysteinemia, 714 BMS patients without hyperhomocysteinemia, and 442 healthy control subjects.
| Group | MCV (fL) | Hb (g/dL) |
Iron (μg/dL) |
Vitamin B12 (pg/mL) | Folic acid (ng/mL) | Homocysteine (μM) | ||
|---|---|---|---|---|---|---|---|---|
| Men | Women | Men | Women | |||||
| BMS patients with hyperhomocysteinemia (n = 170) | 91.7 ± 8.5 | 13.9 ± 1.7 (n = 69) | 12.5 ± 1.3 (n = 101) | 81.2 ± 23.4 (n = 69) | 84.6 ± 30.0 (n = 101) | 382.0 ± 233.2 | 11.8 ± 6.0 | 15.8 ± 5.4 |
| aP-value | 0.008 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| bP-value | <0.001 | <0.001 | <0.001 | <0.001 | 0.109 | <0.001 | <0.001 | <0.001 |
| BMS patients without hyperhomocysteinemia (n = 714) | 89.1 ± 6.9 | 14.9 ± 1.2 (n = 143) | 13.2 ± 1.1 (n = 571) | 97.8 ± 26.7 (n = 143) | 90.1 ± 32.0 (n = 571) | 700.9 ± 237.7 | 15.0 ± 7.6 | 7.7 ± 1.9 |
| aP-value | <0.001 | 0.138 | <0.001 | 0.035 | <0.001 | 0.632 | 0.475 | <0.001 |
| Healthy control subjects (n = 442) | 90.4 ± 3.6 | 15.1 ± 0.8 (n = 106) | 13.5 ± 0.7 (n = 336) | 105.2 ± 28.0 (n = 106) | 97.8 ± 27.2 (n = 336) | 694.2 ± 220.2 | 14.7 ± 5.7 | 8.3 ± 2.0 |
a
Comparisons of means of parameters between 170 BMS patients with hyperhomocysteinemia or 714 BMS patients without hyperhomocysteinemia and 442 healthy control subjects by Student's t-test.
b
Comparisons of means of parameters between 170 BMS patients with hyperhomocysteinemia and 714 BMS patients without hyperhomocysteinemia by Student's t-test.