Table 2.
Comparisons of frequencies of microcytosis (mean corpuscular volume or MCV < 80 fL), macrocytosis (MCV ≥ 100 fL), blood hemoglobin (Hb) and serum iron, vitamin B12, and folic acid deficiencies, and gastric parietal cell antibody (GPCA) positivity between any two of three groups of 170 burning mouth syndrome (BMS) patients with hyperhomocysteinemia, 714 BMS patients without hyperhomocysteinemia, and 442 healthy control subjects.
| Group | Patient number (%) |
||||||
|---|---|---|---|---|---|---|---|
| Microcytosis (MCV < 80 fL) | Macrocytosis (MCV ≥ 100 fL) | Hb deficiency (Men < 13 g/dL, women < 12 g/dL) | Iron deficiency (<60 μg/dL) | Vitamin B12 deficiency (<200 pg/mL) | Folic acid deficiency (<4 ng/mL) | GPCA positivity | |
| BMS patients with hyperhomocysteinemia (n = 170) | 9 (5.3) | 28 (16.5) | 77 (45.3) | 39 (22.9) | 35 (20.6) | 14 (8.2) | 32 (18.8) |
| aP-value | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 | <0.001 |
| bP-value | 0.252 | <0.001 | <0.001 | 0.011 | <0.001 | <0.001 | 0.006 |
| BMS patients without hyperhomocysteinemia (n = 714) | 59 (8.3) | 18 (2.5) | 98 (13.7) | 104 (14.6) | 7 (1.0) | 6 (0.8) | 77 (10.8) |
| aP-value | <0.001 | 0.002 | <0.001 | <0.001 | 0.090 | 0.131 | <0.001 |
| Healthy control subjects (n = 442) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (1.8) |
Comparisons of frequencies of parameters between 170 BMS patients with hyperhomocysteinemia or 714 BMS patients without hyperhomocysteinemia and 442 healthy control subjects by chi-square test.
Comparisons of frequencies of parameters between 170 BMS patients with hyperhomocysteinemia and 714 BMS patients without hyperhomocysteinemia by chi-square test.