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. 2020 Jun 20;78:100738. doi: 10.1016/j.jbior.2020.100738

Table 1.

Drugs currently used to treat COVID-19.

DRUG MODE OF ACTION ORIGINALLY USED TO TREAT REFRENCES
Chloroquine/Hydrochloroquine Inhibit SARS-CoV-2 entry by changing glycosylation of ACE2 receptor. Malaria and arthritis. (Liu et al., 2020; Olofsson et al, 2020; Pahan and Pahan, 2020)
Remdesivir Inhibition of RNA genome replication. Ebola. Mullard (2020)
Lopinavir/ritonavir Protease inhibition HIV. Godfrey et al. (2020)
Favipiravir A broad spectrum inhibitor of viral RNA polymerase. Influenza. (Furuta et al., 2017; Srinivas et al., 2020)
Azithromycin Interferes with protein synthesis. Bacterial conjunctivitis. Diaz et al, 2020
Doxycyclin Inhibits bacterial protein synthesis. Antibiotic against gram + and gram – bacteria. van Velzen et al. (2020)
Ivermectin Inhibits importin mediated viral import. Nematode and orthropod parasites. Choudhary et al. (2020)