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Effects of GRWE on locomotor activity in the open field test after CUMS procedure. Data are presented as mean ± SEM (n = 12). Data were analyzed by t-test and one-way ANOVAs, followed by Tukey's post hoc test. #P < 0.05 vs. the control group; ∗P < 0.05 and ∗∗P < 0.01 vs. the CUMS group. CUMS: chronic unpredictable mild stress; GRWE: Gastrodiae Rhizoma water extract; FH: fluoxetine hydrochloride; SEM: standard error of the mean.
