Figure 7.

The effect of RLT-03 on tumor tissue necrosis and expression of RTK ligands and inflammatory factors. (a) HE staining. The RLT-03 group exhibited tumor tissue necrosis. (b) CD34, EGF, VEGF, IL-10, and TGF-β expression and TUNEL staining were examined in tumor tissue. The expression of CD34, EGF, VEGF, IL-10, and TGF-β was inhibited, and RLT-03 induced tumor cell apoptosis (p < 0.05^∗). Magnification: 400x. (c) As shown by western blotting, EGF, VEGF, and TGF-β protein expressions were inhibited in tumor tissue (p < 0.05^∗).