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. 2020 Jun 5;22(6):e15845. doi: 10.2196/15845

Table 3.

Primary outcome analysis with imputed data (N=221): intervention comparisons along the follow-up.

Primary outcome Time 1 (pretreatment) Time 2 (posttreatment) Time 3 (6 months) Time 4 (12 months)
PHQ-9a

iTAUb vs HLPc


gd 0.25 –0.50 –0.22 –0.06


P value .20 .01 e .23 .73


βf (95% CI) 1.41 (–0.75 to 3.57) –3.05 (–5.43 to –0.68) –1.52 (–3.98 to 0.95) –0.40 (–2.71 to 1.91)

iTAU vs MPg


g –0.17 0.47 0.24 –0.01


P value .36 .01 .18 .96


β (95% CI) 1.00 (–1.16 to 3.16) –3.00 (–5.37 to –0.63) –1.68 (–4.15 to 0.78) 0.06 (–2.25 to 2.37)

iTAU vs PAPPh


g –0.23 0.23 0.31 0.01


P value .20 .22 .10 .99


β (95% CI) 1.40 (–0.74 to 3.54) –1.46 (–3.81 to 0.89) –2.08 (–4.52 to 0.37) –0.02 (–2.31 to 2.27)

HLP vs MP


g 0.07 -0.01 0.03 –0.07


P value .71 .96 .90 .70


β (95% CI) 0.41 (–1.78 to 2.57) –0.06 (–2.46 to 2.35) 0.17 (–2.33 to 2.67) –0.46 (–2.81 to 1.88)

HLP vs PAPP


g 0.00 –0.25 0.09 –0.06


P value .99 .19 .66 .75


β (95% CI) 0.01 (–2.16 to 2.18) –1.59 (–3.97 to 0.79) 0.56 (–1.92 to 3.04) –0.38 (–2.70 to 1.94)

MP vs PAPP


g –0.07 –0.23 0.06 0.01


P value .72 .21 .76 .94


β (95% CI) 0.40 (–1.77 to 2.57) 1.53 (–0.85 to 3.92) –0.39 (–2.87 to 2.08) –0.08 (–2.41 to 2.24)

aPHQ-9: Patient Health Questionnaire-9 items.

biTAU: improved treatment as usual.

cHLP: healthy lifestyle program.

dg: Hedge’s effect size measure.

eStatistically significant values (P<.05) are shown in italics.

fβ: regression coefficient.

gMP: mindfulness program.

hPAPP: positive affect promotion program.