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. 2020 Jan 13;102(5):1055–1064. doi: 10.1093/biolre/ioaa008

Figure 6.

Figure 6

Immunohistochemical analysis of (A) Ki67 as a marker of cell proliferation, KRT14 as a marker of epithelial cells, and WT1 as a marker of cancer cells (black arrows show hyperplastic OSE at 2 months), (B) PAX8 as a marker of oviductal epithelial cells in Ptend/d Trp53d/d Cdh1d/d TgK19GT121 mice. Similar staining was observed in Ptend/d Trp53d/d TgK19GT121 (data not shown). (C) CDH1 (white arrows show CDH1 positive cells) in control, Ptend/d Trp53d/d TgK19GT121, and Ptend/d Trp53d/d Cdh1d/d TgK19GT121 mice. (D) Immunohistochemical analysis of Ki67, KRT14, and WT1 in metastatic tumors.