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In vitro anti-WEEV (strain California) and anti-EEEV (strain FL93–939) activity of BDGR-4
| WEEV EC501 (nM) |
WEEV log titer reduction2 |
EEEV EC50 (nM) |
EEEV log titer reduction |
|
|---|---|---|---|---|
| BDGR-4 | 102.3 ± 37.8 | > 6.24* | 149.5 ± 24 | ND |
cytopathic effect (CPE) assay in VERO76 cells;
done at 18 h post infection using 5 μM compound concentration in VERO76 cells. ;
No progeny virus plaques were detected. ND = not determined.
