Table 2.
SNHG12 Expression and Clinicopathologic Features in 80 Cases of DLBCL
| Variables | Total (n=80) | SNHG12, n (%) | P-value | |
|---|---|---|---|---|
| High Expression (n=40) | Low Expression (n=40) | |||
| Age, year | ||||
| <60 | 39 | 21 (52.5) | 18 (45.0) | 0.502 |
| ≥60 | 41 | 19 (47.5) | 22 (55.0) | |
| Gender | ||||
| Male | 40 | 24 (54.5) | 16 (44.4) | 0.369 |
| Female | 40 | 20 (45.5) | 20 (55.6) | |
| B symptoms | ||||
| Absent | 40 | 19 (57.6) | 21 (44.7) | 0.256 |
| Present | 40 | 14 (42.4) | 26 (55.3) | |
| Stages | ||||
| I-II | 45 | 16 (40.0) | 29 (72.5) | 0.003 |
| III-IV | 35 | 24 (60.0) | 11 (27.5) | |
| Extra-nodal invasion | ||||
| Yes | 49 | 30 (75.0) | 19 (47.5) | 0.012 |
| No | 31 | 10 (25.0) | 21 (52.5) | |
| Serum LDH | ||||
| <300 | 39 | 14 (35.0) | 25 (62.5) | 0.014 |
| ≥300 | 41 | 26 (65.0) | 15 (37.5) | |
| IPI score | ||||
| 0–2 | 31 | 14 (35.0) | 17 (42.5) | 0.491 |
| 3–5 | 49 | 26 (65.0) | 23 (57.5) | |
Note: P < 0.05 is showed in bold.
Abbreviations: DLBCL, diffuse large B-cell lymphoma; LDH, lactate dehydrogenase; IPI, International Prognostic Index.