Table 3.
Univariate and Multivariate Analyses for Overall Survival in 80 Cases of DLBCL
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age, ≥60 vs <60 | 1.082(0.694–1.796) | 0.674 | ||
| Gender, male vs female | 1.101(0.799–1.556) | 0.565 | ||
| B symptoms, present vs absent | 1.355(0.778–2.335) | 0.089 | ||
| Stages, III–IV vs I–II | 1.456(1.234–1.656) | <0.001 | 1.334(1.210–1.598) | 0.002 |
| Extra-nodal invasion, yes vs no | 1.543(0.834–1.845) | 0.210 | ||
| Serum LDH, ≥300 vs <300 | 1.482(0.821–1.898) | 0.121 | ||
| IPI score, 3–5 vs 0–2 | 1.897(1.667–2.120) | 0.010 | 1.776(1.554–2.012) | 0.034 |
| SNHG12 expression, high vs low | 1.319(1.180–1.510) | 0.009 | 1.232(1.128–1.434) | 0.003 |
Note: P < 0.05 is showed in bold.
Abbreviations: DLBCL, diffuse large B-cell lymphoma; LDH, lactate dehydrogenase; IPI, International Prognostic Index.