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. 2020 Jun 12;15:4151–4169. doi: 10.2147/IJN.S246447

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© 2020 Xiong et al.

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In vivo FUS ablation. (a-f) Different concentrations of APS/AuNRs/PLGA-PEG + FUS groups: (0 mg/mL, 1 mg/mL, 2 mg/mL, 3 mg/mL, 4 mg/mL, 5 mg/mL), 3 rabbits per group. (A) Rabbit liver after ablation. (B) Necrosis area analysis. (Insert: Maximum longitudinal section of necrotic tissue.) (C) Corresponding energy efficiency factor (EEF). All statistical analyses were in comparison to the control group. **P< 0.01, ***P< 0.001, ****P< 0.0001.

Abbreviations: APS, astragalus polysaccharide; AuNRs, gold nanorods; PLGA, poly(lactic-co-glycolic) acid; PEG, polyethylene glycol; FUS, focused ultrasound.