Fig. 4.

Effects of SAMC on lung morphometric changes in the LPS-induced ARDS mice. Sections are shown for the HE staining with the magnification of 100. Study groups: C: control group, orally treated with the vehicle only; M: model group, LPS was instilled into the lungs of mice through a high-pressure syringe; L and H: orally treated with SAMC 20 and 40 mg/kg after the LPS challenge, respectively; P: positive control, NAC dosed at 500 mg/kg; n = 5 per group. *** p < 0.001 compared with the control group; ## p < 0.01, ### p < 0.001 compared with the model group. The data are represented as means ± SD.