Table 4.
Comparison of lymphocyte subsets, cytokines and CT lesion volume in peripheral blood between mild and severe patients.
| All patients |
Mild group |
Severe group |
P-value | ||||
|---|---|---|---|---|---|---|---|
| n | Median (IQR) | n | Median (IQR) | n | Median (IQR) | ||
| Lymphocytes, ×109/l | 93 | 1.1 (0.7) | 60 | 1.25 (0.63) | 33 | 0.9 (0.5) | 0.0001 |
| CD3+T cell, /μl | 73 | 715.5 (577.13) | 48 | 821.86 (526.19) | 25 | 465.28 (505.67) | 0.0011 |
| CD4+T cell, /μl | 73 | 403.5 (258.8) | 48 | 475.68 (263.57) | 25 | 277.07 (306.09) | 0.001 |
| CD8+T cell, /μl | 73 | 260.11 (252.78) | 48 | 302.35 (256.25) | 25 | 185.75 (166.3) | 0.0062 |
| B cell, /μl | 73 | 151.36 (121.25) | 48 | 146.37 (136.01) | 25 | 154.06 (89.84) | 0.6811 |
| NK cell, l/μl | 73 | 198.28 (137.65) | 48 | 212.47 (160.21) | 25 | 176.25 (123.55) | 0.1907 |
| CD4+T/CD8+T | 73 | 1.58 (0.97) | 48 | 1.68 (0.9) | 25 | 1.46 (0.96) | 0.4376 |
| IL-2, pg/ml | 93 | 1.3 (1.14) | 60 | 1.35 (1.16) | 33 | 1.07 (0.55) | 0.1202 |
| IL-4, pg/ml | 93 | 1.63 (1.08) | 60 | 1.67 (1.06) | 33 | 1.52 (0.91) | 0.5513 |
| IL-6, pg/ml | 93 | 5.97 (12.81) | 60 | 4.63 (11.58) | 33 | 12.66 (22.01) | 0.0427 |
| IL-10, pg/ml | 93 | 3.55 (3.38) | 60 | 3.49 (2.13) | 33 | 4.93 (6.13) | 0.011 |
| TNF-α, pg/ml | 93 | 1.26 (1.11) | 60 | 1.36 (1.3) | 33 | 1.13 (0.77) | 0.1164 |
| IFN-γ, pg/ml | 93 | 2.02 (1.53) | 60 | 1.99 (1.64) | 33 | 2.1 (1.51) | 0.7734 |
| CT lesion volume, cm3 | 93 | 119.65 (302.16) | 60 | 80.49 (145.51) | 33 | 334.25 (396.13) | 0.0001 |