Table 1.
Baseline main characteristics of study population according to ECG abnormalities documented during hospitalization for COVID-19 pneumonia.
| Variable | Overall | New ECG changes | p | |
|---|---|---|---|---|
| (N = 50) | No (N = 37) | Yes (N = 13) | ||
| Age (years) | 64±15 | 64±12 | 65±20 | 0.776 |
| Sex (male,%) | 72 | 68 | 85 | 0.239 |
| BMI (Kg/m2) | 26.8 ± 4.4 | 27.4 ± 4.2 | 25.4 ± 4.7 | 0.157 |
| Systolic BP (mmHg) | 126±19 | 126±19 | 126±18 | 0.957 |
| Diastolic BP (mmHg) | 80±12 | 82±11 | 74±11 | 0.051 |
| Pulse pressure (mmHg) | 46±14 | 44±14 | 49±15 | 0.300 |
| Hypertension (%) | 50 | 46 | 62 | 0.333 |
| Current smoker (%) | 10 | 8 | 15 | 0.705 |
| Diabetes (%) | 12 | 14 | 8 | 0.578 |
| Coronary artery disease (%) | 10 | 8 | 15 | 0.452 |
| Heart failure (%) | 6 | 3 | 15 | 0.098 |
| COPD (%) | 2 | 3 | 0 | 0.549 |
| Antiretroviral (%) | 54 | 68 | 15 | 0.001 |
| Hydroxychloroquine (%) | 82 | 89 | 62 | 0.026 |
| Macrolides (%) | 56 | 57 | 54 | 0.856 |
| Enoxaparin (%) | 76 | 78 | 69 | 0.506 |
| RAS blockers (%) | 18 | 19 | 15 | 0.081 |
| PaO2/FIO2 ratio (mmHg) | 346±111 | 349±121 | 336±77 | 0.708 |
| pH | 7.44±0.03 | 7.45±0.02 | 7.44±0.04 | 0.437 |
| Hemoglobin (g/dl) | 12.6 ± 1.3 | 12.7 ± 1.2 | 12.3 ± 1.6 | 0.414 |
| White blood cell count (x103) | 7.0 ± 2.9 | 7.2 ± 2.8 | 6.3 ± 3.0 | 0.328 |
| Creatinine (mg/dl) | 0.83±0.22 | 0.80±0.15 | 0.90±0.3 | 0.063 |
| Potassium (mEq/l) | 4.3 ± 0.4 | 4.3 ± 0.5 | 4.3 ± 0.4 | 0.806 |
| CRP (mg/dl) | 3.1 ± 3.8 | 3.0 ± 3.8 | 3.5 ± 3.8 | 0.639 |
| HS-troponin I (pg/ml) | 8.04±9.45 | 7.18±8.32 | 10.72±12.38 | 0.264 |
| Blood urea nitrogen (mg/dl) | 35.2 ± 18.5 | 33.9 ± 16.9 | 38.2 ± 22.6 | 0.513 |
| Heart rate (/min) | 75±17 | 76±16 | 73±21 | 0.547 |
| PR interval (msec) | 164±26 | 161±18 | 173±41 | 0.178 |
| QRS duration (msec) | 99±13 | 98±12 | 101±16 | 0.532 |
| QTc (msec) | 428±26 | 427±23 | 432±36 | 0.533 |
| ST-T abnormalities (%) | 30 | 27 | 38 | 0.439 |
| LV hypertrophy (%) | 33 | 31 | 40 | 0.318 |
Legend: ECG=electrocardiographic; BMI=body mass index; BP=blood pressure; COPD=chronic obstructive pulmonary disease; RAS=renin-angiotensin system; CRP=C-reactive protein; HS=high sensitivity; LV=left ventricular. Normal value of HS-troponin I<15.6 pg/ml.