Table 2.

Univariate and Multivariate Analyses for Overall Survival on NSCLC Patients treated with Neoadjuvant Chemotherapy

Characteristics	No. of Patients	HR (95% Cl)	P Value
A. Univariate Cox Model
Age (Continuous)	151	1.01 (0.98–1.04)	0.53
Gender			0.51
Female (Reference)	76	1.00
Male	75	1.17 (0.73–1.89)
Histology			0.35
Adenocarcinoma (Reference)	96	1.00
Squamous Cell Carcinoma	51	1.23 (0.74–2.04)	0.42
Other	4	2.02 (0.72–5.65)	0.18
Post-Surgical Stage			<0.0001
0/IA/IB (Reference)	44	1.00
IIA/IIB	44	1.86 (0.89–3.89)	0.1
IIIA/IIIB	60	2.96 (1.52–5.77)	0.001
IV	3	17.75 (4.76–66.18)	<0.0001
MPR (Observer 1)			0.001
(+) ≤10%	33	1.00
(−) >10%	118	3.36 (1.60–7.05)
MPR (Observer 2)			0.001
(+) ≤10%	33	1.00
(−) >10%	118	3.31 (1.59–7.12)
B. Multivariate Cox Model
Post-Surgical Stage			0.001
0/IA/IB (Reference)	44	1.00
IIA/IIB	44	1.51 (0.71–3.20)	0.28
IIIA/IIIB	60	2.34 (1.18–4.65)	0.02
IV	3	12.80 (3.39–48.38)	<0.0001
MPR (Observer 1)			0.01
(+) ≤10%	33	1.00
(−) >10%	118	2.68 (1.25–5.73)
MPR (Observer 2)			0.01
(+) ≤10%	33	1.00
(−) >10%	118	2.72 (1.22–5.70)

Abbreviations: HR, Hazard Ratio; CI, Confidence Interval. (AJCC7)