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TREM2 overexpression modifies microglia phenotype in VD mice. (a) IHC staining of M1 microglia phenotype marker iNOS and M2 microglia phenotype marker Arg-1 in the hippocampus of VD mice. Scale bars = 50 μm. (b–e) Western blot analysis of iNOS and Arg-1 protein level in the hippocampus of VD mice. Compared to the sham group, ∗p < 0.05; compared to the LV-control group, #p < 0.05.
