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. 2020 Jun 21;178:114114. doi: 10.1016/j.bcp.2020.114114

Table 1.

Cardiovascular (CV) comorbidities and complications in patients with COVID-19.

Cases Hospital Age Cardiovascular comorbidity Cardiovascular complications Ref
41 Jinyintan Hospital 49 (41–58) CVD (15%), hypertension (15%) Acute cardiac injury* (12%) [7]
138 Zhongnan Hospital 56 (42–68) Hypertension (31.2%), CVD (14.5%), cerebrovascular (5.1%) Acute cardiac injury (7.2%), shock (8.7%) and arrhythmia (16.7%) [6]
1099 552 Hospitals in China 47 (35–58) Hypertension (15%), CAD (2.5%), cerebrovascular (1.4%) Creatine kinase ≥ 200 U/L (13.7%), and septic shock (1.1%) [11]
21 Evergreen Hospital 70 (43–92) Congestive heart failure (42.9%), troponin level > 0.3 ng/mL (14%) Cardiomyopathy** (33.3%) [29]
137 9 Tertiary Hospitals in Hubei 57 (20–83) Hypertension (9.5%) and CVD (7.3%) Symptom of heart palpitation (7.3%) and comorbid organ dysfunction (18.9%) [22]
149 3 Tertiary Hospitals Wenzhou 45 (32–58) Cardio-cerebrovascular disease (18.79%) Symptoms of Chest pain (3.36%) and chest tightness (10.74%), increased creatine kinase (8.05%) [88]
140 No.7 Hospital of Wuhan 57 (25–87) Hypertension (30%), CAD (5%), hyperlipidemia (5%), arrhythmia (3.6%), stroke (2.1%), aorta sclerosis (1.4%) Symptom of dyspnea/chest tightness (36.7%), increased creatine kinase (6.7%) [89]
80 3 Hospitals in Jiangsu 46 (31–62) CVD and cerebrovascular disease (31.25%) Symptom of chest pain (3.75%) and increased creatine kinase-MB (20%) [90]
187 The 7th Hospital of Wuhan 59 (44–73) Hypertension (32.6%), coronary heart disease (11.2%), and cardiopathy (4.3%) Myocardial injury (27.8%), ventricular tachycardia/ fibrillation (5.9%), acute coagulopathy (34.1%) [24]

*Acute cardiac injury is defined as the increased of biomarkers of myocardial injury or new abnormalities in electrocardiogram and echocardiogram. **Cardiomyopathy is defined as decreased of left ventricular ejection fraction to clinical symptoms of cardiogenic shock, an increase of myocardial biomarkers, or a decrease of central venous oxygen saturation (<70%) with no past history of contraction dysfunction.