Figure 1.

Schematic of experimental design. Female Japanese macaques were placed on CON or WSD for 2–7 years prior to pregnancy and maintained on the same diet through pregnancy and weaning of offspring. Postweaning, offspring were either maintained on the same diet or switched to the alternate diet. Fetal samples were assayed at g130, juveniles were assayed at 14 months of age (14mo), and skeletal muscle biopsies were assayed from animals at 7 months of age (7mo).