. 2020 Jun 20;17:196. doi: 10.1186/s12974-020-01867-5

Table 3.

Laboratory data NLRP3-, MEFV-, and TNFRSF1A low-penetrance variants

	All	NLRP3 variants w/o MS	NLRP3 variants with MS	MEFV variants w/o MS	MEFV variants with MS	TNFRSF1A variants w/o MS	TNFRSF1A variants with MS
CRP (mg/dl)	2.7 ± 1.6 (54) (0.6-86)	2.2 ± 2.0 (7) (0.6-10.1)	2.1 ± 1.2 (3) (0.8-2.8)	4.7 ± 8.9 (10) (0.65-86)	1.7 ± 1.5 (16) (0.6-11.5)	0.7 ± 0.1 (2) (0.7-0.8)	4.7 ± 6.6 (16) (0.6-23.8)
Leucocytes (G/l)	13.3 ± 0.6 (36) (10.5–31.9)	13.5 ± 2.4 (6) (10.3–29)	14.1 ± 3.1 (4) (10.7–31.9)	13.2 ± 1.5 (7) (11.1–19.3)	12.5 ± 2.1 (8) (10.5–16.6)	-	13.0 ± 2.1 (11) (11.3-18.6)
SAA (mg/dl)	31 ± 36.2 (68) (5.2-3115)	172.2 ± 492.9 (11) (5.2-3115)	21.7 ± 32.8 (8) (5.2-107)	10.5 ± 5.1 (9) (6.0-22.1)	95 ± 298.2 (14) (5.2-1130)	9.4 ± 3.0 (5) (5.7-13-1)	18.4 ± 25 (21) (5.2-122)

All

NLRP3
variants w/o MS

NLRP3
variants with MS

MEFV
variants w/o MS

MEFV
variants with MS

TNFRSF1A
variants w/o MS

TNFRSF1A
variants with MS

CRP (mg/dl)

2.7 ± 1.6 (54)

(0.6-86)

2.2 ± 2.0 (7)

(0.6-10.1)

2.1 ± 1.2 (3)

(0.8-2.8)

4.7 ± 8.9 (10)

(0.65-86)

1.7 ± 1.5 (16)

(0.6-11.5)

0.7 ± 0.1 (2)

(0.7-0.8)

4.7 ± 6.6 (16)

(0.6-23.8)

Leucocytes (G/l)

13.3 ± 0.6 (36) (10.5–31.9)

13.5 ± 2.4 (6)

(10.3–29)

14.1 ± 3.1 (4)

(10.7–31.9)

13.2 ± 1.5 (7)

(11.1–19.3)

12.5 ± 2.1 (8)

(10.5–16.6)

13.0 ± 2.1 (11)

(11.3-18.6)

SAA (mg/dl)

31 ± 36.2 (68)

(5.2-3115)

172.2 ± 492.9 (11)

(5.2-3115)

21.7 ± 32.8 (8)

(5.2-107)

10.5 ± 5.1 (9)

(6.0-22.1)

95 ± 298.2 (14)

(5.2-1130)

9.4 ± 3.0 (5)

(5.7-13-1)

18.4 ± 25 (21)

(5.2-122)

Numbers represent mean ± SD (sample size) and (range). CRP C-reactive protein (normal up to 0.5 mg/dl); leucocytes (normal up to 10.4G/l); SAA serum amyloid-a (normal up to 5.0 mg/l)