Fig. 7.

a,b: Presentation of the VBM results produced by the SPM12 software with the SPMMouse plugin for grey matter of control versus mdx at various time points. The grey matter average shown is for the control mice and a coloured overlay showing the location of significant clusters. Red clusters indicate where control mouse brain is larger than mdx brain and blue indicates where mdx brain is larger than control brain. Colour intensity on the scale bar refers to the level of significance with a lighter colour indicating a higher level of significance (p < 0.05, student's t-test). a. Coronal images numbered 1–5 with corresponding sagittal image detailed image plane. (Grey matter average is from 8 control mice). b. Axial grey matter slices detailing VBM findings.