Table 2.

Effect of tranexamic acid on death due to bleeding and rebleeding

	Tranexamic acid (n=5956)	Placebo (n=5981)	Risk ratio (95% CI)
Death due to bleeding within 24 h	124 (2·1%)	120 (2·0%)	1·04 (0·81–1·33)
Death due to bleeding within 5 days	222 (3·7%)	226 (3·8%)	0·99 (0·82–1·18)
Death due to bleeding within 28 days	253 (4·2%)	262 (4·4%)	0·97 (0·82–1·15)
Rebleeding within 24 h*	41 (0·7%)	41 (0·7%)	1·00 (0·65–1·55)
Rebleeding within 5 days*	287 (4·8%)	315 (5·3%)	0·91 (0·78–1·07)
Rebleeding within 28 days*	410 (6·8%)	448 (7·5%)	0·92 (0·81–1·05)

Data are n (%) and risk ratio (95% CI). Death or rebleeding in hospital during follow-up.

^*Excludes 13 patients missing data on rebleed status or rebleed date.