Table 4.
Correlation between Assays for humoral response.
| Assay 1 | Assay 2 | Time | Correlation* |
|---|---|---|---|
| IgG against ZEBOV GP (concentration) | NAb against ZEBOV GP | 0 | 0.08 |
| IgG against ZEBOV GP (concentration) | NAb against ZEBOV GP | 28 | 0.44 |
| IgG against ZEBOV GP (concentration) | IgG against whole virion | 0 | 0.30 |
| IgG against ZEBOV GP (concentration) | IgG against whole virion | 28 | 0.52 |
| IgG against ZEBOV GP (concentration) | NAb against whole virion | 0 | 0.35 |
| IgG against ZEBOV GP (concentration) | NAb against whole virion | 28 | 0.40 |
| NAb against ZEBOV GP | IgG against whole virion | 0 | N/A |
| NAb against ZEBOV GP | IgG against whole virion | 28 | 0.16 |
| NAb against ZEBOV GP | NAb against whole virion | 0 | N/A |
| NAb against ZEBOV GP | NAb against whole virion | 28 | 0.34 |
| IgG against whole virion | NAb against whole virion | 0 | −0.02 |
| IgG against whole virion | NAb against whole virion | 28 | 0.48 |
*
Spearman rank correlation coefficient estimated for those whose antibody response was available for per-protocol analysis by both assays.