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. Author manuscript; available in PMC: 2020 Jun 21.
Published in final edited form as: Biochemistry. 2020 Apr 30;59(19):1800–1803. doi: 10.1021/acs.biochem.0c00091

Figure 1.

Figure 1.

TEM images of in vitro (a) and ex vivo (b) TTR amyloid. The in vitro TTR amyloid was obtained by incubating recombinantly-generated monomeric TTR (mTTR; F87M/L110M) at a protein concentration of 0.5 mg/ml in PBS buffer (pH 7.4) at 37 °C for two days. The ex vivo TTR amyloid was extracted from human cardiac tissue (TTRwt).