Table 1.
CTL | CD | REC | All other | CD versus CTL: t (P) | |
---|---|---|---|---|---|
Age | 28.6 ± 3.9 | 28.6 ± 3.5 | 28.3 ± 3.9 | 28.9 ± 3.7 | 0.02 (0.98) |
Sex (% male) | 64/89 (72%) | 64/89 (72%) | 48/87 (55%) | 375/941 (40%) | |
BMI | 27.5 ± 5.2 | 26.8 ± 4.8 | 26.6 ± 6.0 | 27.1 ± 6.0 | −0.96 (0.34) |
Edu | 14.3 ± 1.8 | 14.3 ± 1.8 | 13.9 ± 2.0 | 15.1 ± 1.8 | −0.04 (0.97) |
DSM depression | 53.6 ± 5.5 | 54.3 ± 7.0 | 54.3 ± 6.1 | 54.0 ± 5.7 | 0.73 (0.47) |
DSM anxiety | 53.1 ± 5.1 | 53.7 ± 6.3 | 53.7 ± 5.4 | 53.3 ± 5.2 | 0.80 (0.43) |
Alcohol (composite Z) | 0.17 ± 0.42 | 0.22 ± 0.46 | 0.14 ± 0.42 | −0.05 ± 0.53 | 0.80 (0.43) |
Tobacco (composite Z) | −0.19 ± 0.56 | 0.79 ± 1.02 | 0.69 ± 1.07 | −0.12 ± 0.80 | 7.94 (<0.001) |
Externalizing problems | 49.4 ± 7.8 | 52.7 ± 10.2 | 53.1 ± 8.5 | 48.1 ± 8.8 | 2.46 (0.02) |
Antisocial behaviors | 53.0 ± 4.5 | 55.1 ± 7.4 | 54.7 ± 5.6 | 52.8 ± 4.5 | 2.22 (0.03) |
Rule-breaking behavior | 53.0 ± 4.2 | 57.9 ± 7.7 | 57.3 ± 6.0 | 53.4 ± 4.7 | 5.28 (<.001) |
Childhood conduct problems | 0.6 ± 0.7 | 1.0 ± 1.0 | 0.7 ± 0.9 | 0.5 ± 0.7 | 2.94 (0.004) |
Note: CTL means control (n = 89); CD, cannabis dependent (n = 89); REC, recreational cannabis users (n = 87); all other = all remaining participants in the HCP (n = 941). CTL and CD are the only 2 groups that are matched, so the 2-sample t-test is reported only for the comparison between these 2 groups. Note that the CTL group is well matched on all variables except for tobacco usage; therefore, tobacco usage was used as a confound regressor in the primary analyses. The externalizing problems, antisocial behaviors, and rule-breaking behaviors are reported as age- and gender-adjusted percentile scores; the childhood conduct problems are scored as part of the SSAGA.