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Quantification of the rhIFN-β transiently expressed by the wild-type and codon-optimized sequence in CHO-s cells at various post-transfection times, based on ELISA. **P ≤ 0.01 and ***P ≤ 0.001 indicate significant differences between 2 groups in each time. CHO-s, suspension adapted Chinese hamster ovary; hIFN-β, the recombinant human interferon beta.
