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DIDS sensitivity of K+-induced alkalinization in HCO3− perfusate. In astrocytes, the K+-induced alkalinization is blocked by addition of 0.5 mM DIDS. In Müller cells, the alkalinization is transformed into an acidification by DIDS. Addition of DIDS also produces an acid shift in steady-state pHi in both astrocytes and Müller cells.
