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. 2020 Jun 5;99(23):e20667. doi: 10.1097/MD.0000000000020667

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Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc.

This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0

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Radiological images of the thoracic lesions (indicated by arrow and circle) before and after systemic treatment in case 3. A. The X-ray showed a bulky mass located in right upper thorax. B. Computed tomography revealed 1 of the pulmonary tumors invading adjacent ribs. C. The other thoracic tumors with osteolytic rib destruction and thickened pleura were shown. D. X-ray indicated a smaller lesion in right upper thorax. E. The tumor showed partial response after 6 months of treatment. E. The other lesions and osteolytic ribs also revealed partial response. CT = computed tomography, PR = partial response.