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. Author manuscript; available in PMC: 2021 Mar 19.
Published in final edited form as: Reprod Toxicol. 2020 Mar 19;92:4–10. doi: 10.1016/j.reprotox.2020.03.006

Figure 3. Omics Scale Measurement of Environmental Chemicals and Metabolic Responses Provides a Foundation for Exposome Epidemiology.

Figure 3.

Untargeted ultra-high resolution mass spectrometry methods are greatly expanding the capabilities to obtain omics scale measures of environmental chemical exposure and associated biologic responses in metabolites and metabolic pathways (Center). Coupled to an expanding range of methods for personal exposure monitoring, including improved geospatial monitoring of air pollution and improved availability of sensors and cell phone apps, these methods are providing epidemiology research with expanded capabilities to test a wide range of exposures and separate contributions of different stressors. Integration of these data with other omics data provide new capabilities to identify associations linked to health and develop predictive models of disease outcome.