Table 4:
Association between urinary biomarkers and acute kidney injury after hematopoietic cell transplant among Validation Cohort N=140
| Odds ratio (95% confidence interval) for acute kidney injury using raw value | Odds ratio (95% confidence interval) for acute kidney injury standardized to creatinine | |
|---|---|---|
| **1CXCL10 >0 pg./ml | 2.50 (1.4–4.55) * | 2.28(1.24–4.18) * |
| 2CXCL9 >200 pg./ml | 2.65(1.17–6) * | 1.02(0.99–1.05) |
| 3NGAL | 1.00(0.99–1.00) | 1.00 (0.99–1.00) |
| 4VCAM | 1.00 (1.00–1.002) * | 1.00(0.99–1.00) |
| 5CCL-2 | 0.99(0.99–0.99) * | 0.99(0.99–1.00) |
| 6IL-18 | 1.00(0.99–1.00) | 1.01(0.98–1.04) |
| 7TWEAK | 1(1–1) | 2.49(1.05–5.9) |
| 8HER | 0.99 (0.99–1.00) | 0.99 (0.98–1.01) |
*
Results statistically significant with a p value<0.006
1
Chemokine (C-X-C motif) ligand 10(CXCL10);
2
Chemokine (C-X-C motif) ligand 9 (CXCL9),
3
Neutrophil gelatinase-associated lipocalin (NGAL);
4
Vascular cell adhesion protein 1 (VCAM-1);
5
C-C motif chemokine ligand 2 (CCL-2)
6
Interleukin 18 (IL-18);
7
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK),
8
Human epidermal growth factor receptor 2 (HER-2)
**
OR are presented for the continuous marker analysis (all quartiles not significant besides CXCL9 and CXCL10 presented with cut off values as well.)