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. Author manuscript; available in PMC: 2021 Mar 1.
Published in final edited form as: Placenta. 2020 Jan 22;92:17–27. doi: 10.1016/j.placenta.2020.01.008

Table 3.

List of the RNA transcripts associated with preeclampsia. Gene symbol, transcript fold change, tissue of origin, study size, gestational age and severity of preeclampsia were included.

Gene symbol Reference Fold change Tissue Study size Gestational Age (preeclampsia, control in weeks) *
PRG2 [32] 6.4 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
FSTL3 [32] 3.7 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
FABP4 [32] 3.5 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
RDH13 [32] 3.1 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
PLAC1 [32] −3.4 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
SERPINI1 [32] −4.4 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
GSTA3 [32] −4.8 syncytiotrophoblasts severe preeclampsia (placenta) 4/4 27,37 ###
CXCL8 [32] 3.5 cytotrophoblasts Severe preeclampsia (placenta) 3/4 27,37 ###
GH2 [32] −14.2 cytotrophoblasts Severe preeclampsia (placenta) 3/4 27,37 ###
miR-210 [24] 2.452 Placenta (full thickness) 16/16 30,29##
37,38#
miR-26a [37] −164.655 Placenta (full thickness) 16/16 ^
miR-376c-3p [71] down Circulating exosomes 5/4 35,35 ^
miR-19a-3p [71] down Circulating exosomes 5/4 35,35 ^
miR-19b-3p [71] down Circulating exosomes 5/4 35,35 ^
miR-885–5p [71] up Circulating exosomes 5/4 35,35 ^
sFLT1 [72] 2.6 Placenta (full thickness) 21/21 34,39 ###
ENG [73] 1.852919237 Placenta (full thickness) 23/37 33,37 ^
INHIBIN A [73]
[74] [75]		 3.0 Placenta (full thickness) 21/21 33,37 ^
SIAE [73] 1.354912795 Placenta (full thickness) 23/37 33, 37 ^
PAPPA2 [73] 2.9 Placenta (full thickness) 21/21 33, 37 ^
BRSK2 [73] 8.6 Placenta (full thickness) 21/21 33, 37 ^
FLJ90650 [73] 10.0 Placenta (full thickness) 21/21 33, 37 ^
LEP [73] 40.0 Placenta (full thickness) 21/21 33, 37 ^
LHB [73] 4.1 Placenta (full thickness) 21/21 33, 37 ^
PDGFD [73] −2.3 Placenta (full thickness) 21/21 33, 37 ^
COX17 [73] −4.3 Placenta (full thickness) 21/21 33, 37 ^
HS3ST2 [74] −1.39  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
TNFRSF14 [74] −1.35 Maternal Placenta (Decidual basalis) 60/65 32,39 ^
SLC2A6 [74] −1.32  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
DPP7 [74] −1.22  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
CD72 [74] −1.21  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
PER3 [74] −1.20  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
DBP [74] −1.20  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
PDK4 [74] 1.72  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
HS3ST2 [74] −1.39  Maternal Placenta (Decidual basalis) 60/65 32,39 ^
##

early-onset preeclampsia

#

late-onset preeclampsia

###

severe preeclampsia

####

mild preeclampsia

^

not specified

*

Type of preeclampsia