TABLE 1.
Sample used to derive voxel‐wise cutoffs
| Characteristics | CU elderly | AD dementia | P value |
|---|---|---|---|
| No. | 296 | 168 | – |
| Age, years, mean (SD) | 71.24 (7.25) | 74.53 (7.6) | <.0001 |
| Female, no. (%) | 153 (51.6) | 83 (49.4) | .63 |
| APOE ε4, no. (%) | 86 (29) | 110 (65.5) | <.0001 |
|
Education, years, mean (SD) |
16.51 (2.65) |
16.04 (2.66) |
.07 |
|
MMSE score (SD) |
28.95 (1.32) |
22.77 (3.09) |
<.0001 |
| [18F]Florbetapir, mean SUVR (SD) | 1.13 (0.24) | 1.36 (0.18) | <.0001 |
P values indicate the values assessed with independent samples t‐tests for each variable except sex and APOE ε4, where contingency χ2 tests were performed.
Abbreviations: AD, Alzheimer's disease; APOE, apolipoprotein E; CU, cognitively unimpaired; MMSE, Mini‐Mental State Examination; SD, standard deviation; SUVR, standardized uptake value ratio