Fig. 2.

Results of SCC improvement (a) Boxplots of colony outgrowth of parental cell lines and DE cell lines. X-axis displays day of analysis after single cell sorting. (b) VCD (blue) and viability (red) of the standard batch experiment with corresponding growth rates (c) and max VCD reached (d). To obtain results in (d) VCD values of K1 8 mM replicate 3 at 190 h was excluded, being an outlier in the measurement. Error bars represent 95% confidence interval. (e) Mean specific productivity (qP) against mean growth rate (µ) DE at the end of the cell line name indicate DE pools. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)