Figure 6.

FKA suppressed the serum lipase levels in CCK-8-induced experimental pancreatitis in BALB/c mice. BALB/c mice were orally administered with FKA (15 or 30 mg/kg in 0.1% DMSO for 2 h) followed by intraperitoneal (i.p.) injections of cholecystokinin-8 (CCK-8). 0.5, 1.5, 2.5, and 4 h after the CCK-8 injections, blood samples were collected from the retroorbital sinus of all mice and serum lipase levels were measured using a commercial serum lipase ELISA kit (R&D System, Minneapolis, MN, USA). Results were represented as the mean ± SD of four experiments. Significant at ^∗∗p < 0.01 compared to the control animals; significant at ^#p < 0.05 compared to the CCK8- administered animals.