Fig.1.

Microphotograph of formalin-fixed tissue from a 79-year-old patient diagnosed with Alzheimer’s disease staining positive using rabbit anti-Ljungan virus VP1 antibodies. Red stain visualizes presence of viral antigen. Panel A is an overview and Panel B is a magnification of the same region of the hippocampus. Red staining marks presence of viral antigen in neurons, astrocytes, and glial cells. In Panel C, an amyloid/neuritic plaque (marked with an arrow) in shown staining positive in the glial compartment and in dystrophic neurites. Panel D shows positive staining in neurons (marked with an arrow).